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Ramadan may be the most times that we suffer from the problem of dry mouth; Due to fasting long hours during the day without food or drink.
But what some people may not know is that dry mouth is a common problem as well during the summer; As a result of increasing fluid loss from the body due to heat and sweating, this can cause discomfort, oral ulcers and tooth decay. So it is necessary to drink sufficient amounts of water in the summer to combat this problem, avoid foods and drinks that cause dehydration, and use saliva alternatives if necessary, available in pharmacies, to moisturize the mouth.
But there is another reason that cannot be overlooked, which can lead to the dry mouth of millions of millions around the world, which is the damage of the salivary glands. These glands are responsible for producing saliva, which in turn plays an important role in moisturizing the mouth and maintaining oral and dental health; And when the salivary glands do not produce enough saliva, dry mouth (Zero Stomia) occurs, which may lead to various health problems.
While the chemotherapy and radiotherapy of head and neck cancer is one of the most common causes of this condition, chronic dry mouth may also occur as a result of aging, the use of certain medications and other factors that include diabetes, stroke, Alzheimer’s and HIV. Unfortunately, there is no cure for this condition.
However, the Mayo Clinic researchers managed to establish the first vital bank in the world to include mini -organic models (organoos) of the tissues of the human salivary glands, which paved the way for research aimed at finding healing treatment.
This important scientific achievement deserves lighting on it, in light of the multiple medical developments that we are witnessing in our time, especially with the intensive and correct use of advanced technology, for the sake of the health and well -being of societies. So let’s get to know more dear, through today’s article, the details of this bank and the hopes it holds for millions of people around the world who suffer from the problem of dry mouth.
What is the vital bank for the regeneration of salivary glands?
Dr. Nagarajan Kanan, the main author, comments in a statement about the study published in the NPJ Regenerative Medicine magazine (NPJ Regenerative Medicine) by saying: “This unique resource of the biological bank overcomes a major obstacle that we have long faced in this field, which is the limited access to standard samples of salivary tissues suitable for the research research research. This group lays the foundation stone for the development of renewal therapy, especially for the condition of dry mouth associated with radiotherapy. ” Dr. Kanan is also the director of the Mayo Clinic Laboratory for stem cell biology and cancer.
It should be noted that about 70% of patients with head and neck cancer who are undergoing radiotherapy suffer from permanent damage in their salivary glands. This results in a decrease in the quality of life due to the constant feeling as if the mouth is lined with cotton. In addition to feeling annoyed, chronic dry mouth can lead to difficulties in chewing, talking and swallowing, as it may cause tooth decay. “This is one of the biggest concerns that I hear from patients with head and neck cancer,” said Dr. Jeffrey Janeos, an ear, otal and throat specialist in Mayo Clinic, Florida and one of the study participants. Unfortunately, commercially available therapeutic solutions are limited to these patients. “
One of the most promising research methods is the cultivation of rare renewable cells in larger numbers, so that they can help people in the future to hospitalize and grow new and sound glands cells. The vital bank consists of samples collected from 208 donors; Thanks, thanks to this warehouse, researchers have already discovered vital indicators of mature cells producing games, and with the help of a high -resolution protein map, they identified the potential histological origin of rare, autonomous, self -regenerative cells.
The research team has also developed a model of a radiological injury, associated with the biological bank, which provides an integrated platform for discovering new and customized biological treatments. This research comes as a fruit of cooperation between the Mayo Clinic Center for Renewal Biological Treatments, the Department of Laboratory Medicine, Pathology and the ENT department, and it is promising, as we have mentioned, for millions who suffer severely from the problem of damage to the salivary glands and its implications for dry mouth.
now; It is necessary to take a deeper look at what the salivary glands are, their functions, problems and how to treat them, in the following lines ..

What are the salivary glands?
The salivary glands are external secretion glands, located around the mouth and secretion of saliva; The latter contains enzymes that help in digestion, also protect the teeth from decay, and maintain the moisture of the mouth. There are several types of salivary glands, such as the main glands and small glands.
1. The main salivary glands:
Parotid Glands: It is located in front of the ears and is the largest salivary glands.
Submandibular Glands: Located under the lower jaw.
Sublingual glands are located under the tongue and are the smallest salivary glands.
2. Small salivary glands:
• It is found throughout the mouth, such as lips, mouth lining, cheeks and throat.
• Helps maintain oral moisture and protect teeth and gums.
What are the functions of salivary glands?
The beautiful thing is that these glands, with saliva, are never simple; Rather, it has important and essential advantages and functions for humans. These jobs are the following:
• Digestion: saliva begins to digest in the mouth thanks to the enzymes it contains, which helps to break the food.
• swallowing: saliva helps moisturize food and facilitate swallowing.
• Oral protection: Games protect the teeth from decay and help prevent the growth of harmful bacteria in the mouth.
• Taste: saliva dissolves food molecules so that the taste buds can recognize flavors.
Speaking: saliva helps in the movement of the tongue and speech.
• Healing: saliva contains factors that help heal wounds in the mouth.
Like other body systems, these glands can be exposed to health problems that result in some health diseases and troubles.
What are the problems of salivary glands?
It is necessary to investigate these problems through a medical examination, and after consulting a specialist. And the problems of salivary glands are four as follows:
1. Salivitis: salivary glands may occur due to infection, salivary channels, or salivary stones.
2. Salivary glands: salivary glands may occur due to inflammation, tumor or stones.
3. Salivary gland tumors: These tumors can be benign or malignant.
4. Dry mouth: dry mouth may occur due to a lack of salivation.
How are salivary gland problems treated?
Treatment depends primarily on the cause of the problem, and it may include:
• Antibiotics in the case of infection.
Pain relievers to reduce pain and swelling.
• Remove obstruction or stones.
• Radiotherapy or surgery in the case of tumors.
• Other treatments recommended by the doctor, to relieve dry mouth.
In summary; Dry mouth, or what is medically known as “Xerostomia”, is a condition that occurs when the amount of saliva produced by the salivary glands decreases, which leads to an annoying feeling of dehydration inside the mouth. This condition may be temporary or chronic, and depends on the underlying cause such as medications or chemical and radiological treatments as well as the damage of the salivary glands.
We need to enhance salivation in the mouth, to do many vital and important functions such as chewing, taste and recovery. So do not help my dear if you suffer from the problem of dry mouth for a long time, I want to consult a specialist to determine the appropriate treatment at the closest opportunity.
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